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Together, the duo starred in their own reality series, “Giuliana and Bill,” and they’ve recently launched a restaurant chain, RPM Italian and RPM Steak with eateries in Chicago and Washington and more on the horizon.

They’re also contemplating a new reality show — they quit the old one when it became too intrusive for their 4-year-old son, Duke — perhaps with a focus on their restaurant business.

This past year alone, more than 40,000 people died of breast cancer, while another 300,000 received the devastating diagnosis and began their own journeys through the storm.

Rancic has become a staple in the entertainment industry, and it's difficult to picture a big Hollywood event without her presence.

An Italian immigrant, this host-with-the-most has worked hard to reach her level of success, and has seemed to stay grounded throughout it all.

“The last thing I want to do is take anything away from the evening,” he said. This is a night for Republicans, Independents, Democrats and anyone with cancer or touched by cancer, because cancer doesn’t discriminate.” Giuliana, a breast cancer survivor who just celebrated her fifth year cancer-free, and Bill are hosting the annual Un Mask Cancer event Oct.

red carpet correspondent Giuliana Rancic, are coming to Boston to host a fundraiser for the Dana-Farber Cancer Institute and Bill knows that The Donald may not be the most popular guy in our blue state.